Botulinum toxin in spastic infantile cerebral palsy: results in 27 cases during one year
R Sanchez-Carpintero, J Narbona - Revista de Neurología, 1997 - europepmc.org
R Sanchez-Carpintero, J Narbona
Revista de Neurología, 1997•europepmc.orgResults The values on PRS improved an average of 24%, adductor angle 66%(p< 0.01),
knee angle 40%(p= 0.05) and ankle angle 52%(p< 0.01); 96% of patients could get more
physiological static or walking patterns because of the decrease of spasticity and those
persisted after the effect of the toxin had worn off. It was maximum at 2 months, stabilized 4
to 6 months later and decreased during further 2 months. Conclusions This experience
leads us to propose higher starting dosage and to take into account the stability of postural …
knee angle 40%(p= 0.05) and ankle angle 52%(p< 0.01); 96% of patients could get more
physiological static or walking patterns because of the decrease of spasticity and those
persisted after the effect of the toxin had worn off. It was maximum at 2 months, stabilized 4
to 6 months later and decreased during further 2 months. Conclusions This experience
leads us to propose higher starting dosage and to take into account the stability of postural …
Results
The values on PRS improved an average of 24%, adductor angle 66%(p< 0.01), knee angle 40%(p= 0.05) and ankle angle 52%(p< 0.01); 96% of patients could get more physiological static or walking patterns because of the decrease of spasticity and those persisted after the effect of the toxin had worn off. It was maximum at 2 months, stabilized 4 to 6 months later and decreased during further 2 months.
Conclusions
This experience leads us to propose higher starting dosage and to take into account the stability of postural pattern of each patient to choice the muscle to be injected. Other therapeutic possibilities are also proposed in children with fixed shortening eg combining the toxin with stretching casts.
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